View topic - Caffeine analogs - Coffee Forum (#)
„Many are stronger then caffeine (1,3-Dipropyl 7-Proparagyl Xanthine is 100 times stronger). Many have stronger effects on A2 then A1 adenosine receptors compared to caffeine. I heard once that antagonizes one of the adenosine receptors caused restlessness and antagonizing the other one caused more desireable stimulation - anyone know which is which? If A2 is better the more selective analogs would likely have cleaner effects than caffeine.“
http://www.coffeeforums.com/ viewtopic.php?t=1058 - Cached
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„Caffeinated clues and the promise of adenosine A2A antagonists in PD Schwarzschild et al. Neurology 2002;58:1154-1160. ABSTRACT | FULL TEXT “
http://jama.ama-assn.org/cgi/content/abstract/283/20/ 2674
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CoffeeGeek - Regional: United States West, I knew drinking Decaf was dumb
„In connection with a study about caffeine's stimulating effects, "Dr. Gilberto Fisone of the Karolinska Institute in Stockholm, Sweden, .noted that caffeine also blocks receptors present in a group of nerve cells involved in neurodegenerative disorders such as Parkinson's disease ( news - web sites).“
http://www.coffeegeek.com/forums/worldregional/uswest/ 2127
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„When the caffeine intake is reduced, the body becomesoversensitive to adenosine. In response, blood pressure drops dramatically, resulting inan excess of blood in the head, leading to the 'caffeine headache.' This headache can lastfrom one to five days, and can be alleviated with an analgesic or with caffeine intake.Further withdrawal symptoms may include irritability, muscle tension, inability toconcentrate or work, and, in extreme cases, nausea and vomiting. Withdrawal symptoms canbegin just 12 hours following your last caffeine indulgence. Symptoms can be counteredwith lots of exercise and sleep.“
http://www.koffeekorner.com/health4.htm
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