JAMA -- Chocolate Consumption and Platelet Function, May 1, 2002, Holt et al. 287 (17): 2212 (#)
„To the Editor: Flavonoid-rich foods and beverages have putative vascular health benefits, including protection against ischemic stroke and reductions in platelet reactivity.1-5 Tea, grapes, apples, and cocoa contain a class of flavonoids known as the flavanols, which includes epicatechin and catechin. Flavanols can polymerize, producing theaflavins and thearubigins (found in tea) and procyanidins (found in grapes, apples, and cocoa). We previously reported reductions in platelet primary hemostasis and glycoprotein IIb/IIIa expression 2 and 6 hours after subjects consumed 300 mL of cocoa containing a total of 897 mg of flavanols and procyanidins.3 We examined whether smaller amounts of chocolate could affect platelet function.“
http://jama.ama-assn.org/cgi/content/extract/287/17/ 2212 - Cached
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„Results A total of 366 women and 204 men had an ischemic stroke. After controlling for standard cardiovascular risk factors, persons in the highest quintile of fruit and vegetable intake (median of 5.1 servings per day among men and 5.8 servings per day among women) had a relative risk (RR) of 0.69 (95% confidence interval [CI], 0.52-0.92) compared with those in the lowest quintile. An increment of 1 serving per day of fruits or vegetables was associated with a 6% lower risk of ischemic stroke (RR, 0.94; 95% CI, 0.90-0.99; P=.01, test for trend). Cruciferous vegetables (RR, 0.68 for an increment of 1 serving per day; 95% CI, 0.49-0.94), green leafy vegetables (RR, 0.79; 95% CI, 0.62-0.99), citrus fruit including juice (RR, 0.81; 95% CI, 0.68-0.96), and citrus fruit juice (RR, 0.75; 95% CI, 0.61-0.93) contributed most to the apparent protective effect of total fruits and vegetables.“
http://jama.ama-assn.org/cgi/content/abstract/282/13/ 1233
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„01). Age-adjusted RR for all stroke, including transient ischemic attack, was 0.78 (95% confidence interval [Cl], 0.62 to 0.98) for each increase of three servings per day. For completed stroke the RR was 0.74 (95% Cl, 0.57 to 0.96); for completed stroke of ischemic origin the RR was 0.76 (95% Cl, 0.57 to 1.02); and for completed stroke of hemorrhagic origin, 0.49 (95% Cl, 0.25 to 0.95). Adjustment for body mass index, cigarette smoking, glucose intolerance, physical activity, blood pressure, serum cholesterol, and intake of energy, ethanol, and fat did not materially change the results.“
http://jama.ama-assn.org/cgi/content/abstract/273/14/ 1113
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„Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration Baldus et al. J. Clin. Invest.“
http://jama.ama-assn.org/cgi/content/abstract/286/17/ 2136
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„Cook on a baking sheet on top of the stove until the apples have started to caramelise. You may need to change this tray a few times during the cooking process but it saves the oven top. Always take great care when dealing with hot liquids and under no circumstances leave it alone.“
http://www.bbc.co.uk/food/recipes/database/ appletartetatin_14399.shtml
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„Comparing it to the other coffees in the cupping is worse than comparing apples and oranges - more like comparing apples and cocker spaniels. The Kaanapali dry-process Moka is, as one panelist called it, a "Yemen wannabe." The trees that produced it are Yemen varietals, and the coffee has been processed in the simple, put-it-out-in-the-sun-to-dry approach used in Yemen and parts of Ethiopia. Which means that, like a Yemen or dry-processed Ethiopia, it is fruity, winy, complex, with a disturbingly lush, overripe aftertaste that lovers of these coffees call gamy or wild and people who don't like Yemen or dry-processed Ethiopia coffees call fermented.Five panelists labeled this coffee fermented and dismissed it with very low scores; three recognized the Yemen/Ethiopia characteristics and treated it like a middle-of-the-road dry-processed Yemen/Ethiopia coffee, giving it scores in the high seventies. Four didn't call it anything but gave it low scores.If this coffee had been presented to the panel in the context of similar dry-processed coffees from Yemen or Ethiopia I don't think it would have provoked quite the same level of criticism.“
http://www.coffeereview.com/review.cfm?id=169
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