JAMA -- Abstract: Clinical experience with theophylline. Relarionships between dosage, serum concentration, and toxicity, May 3, 1976, Jacobs et al. 235 (18): 1983 (#)
„Fourteen patients (30%) had a toxic reaction to theophylline. Toxic symptoms, which were not always gastrointestinal, occurred commonly with serum concentrations over 25 mug/ml but were not noted with concentrations below 15 mug/ml. High serum theophylline concentrations and a toxic reaction developed just as often with the oral route as when the drug was given intravenously. In six patients, measurement of serum theophylline concentration disclosed subtherapeutic concentrations.“
http://jama.ama-assn.org/cgi/content/abstract/235/18/ 1983 - Cached
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„Paradoxical decrease of mitochondrial DNA deletions in epithelial cells of active ulcerative colitis patients Fukushima and Fiocchi Am. Physiol. 2004;286:G804-G813. ABSTRACT | FULL TEXT “
http://jama.ama-assn.org/cgi/content/abstract/266/13/ 1812
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- Coffee Science Information Centre
„Some particularly sensitive people may suffer mild symptoms of withdrawal after sudden abstention from coffee drinking. A 150 ml cup of instant coffee contains about 60mg caffeine and filter coffee contains about 85 mg. For those who like coffee but are sensitive to caffeine, the decaffeinated beverage contains only 3 mg per cup.“
http://www.cosic.org/coffee-and-health/summary
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„Association of Coffee Consumption with Gallbladder Disease Ruhl and Everhart Am. Epidemiol. 2000;152:1034-1038. ABSTRACT | FULL TEXT “
http://jama.ama-assn.org/cgi/content/abstract/281/22/ 2106
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„Transfer of particulate matter pollution from smoking to non-smoking coaches: the explanation for the smoking ban on Italian trains Invernizzi et al. Tob Control 2004;13:319-320. FULL TEXT “
http://jama.ama-assn.org/cgi/content/abstract/287/9/ 1132
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